{"id":6621,"date":"2015-02-14T15:42:39","date_gmt":"2015-02-14T20:42:39","guid":{"rendered":"https:\/\/spinor.info\/weblog\/?p=6621"},"modified":"2015-02-14T15:42:39","modified_gmt":"2015-02-14T20:42:39","slug":"the-simple-math-of-herd-immunity","status":"publish","type":"post","link":"https:\/\/spinor.info\/weblog\/?p=6621","title":{"rendered":"The simple math of herd immunity"},"content":{"rendered":"<p>Vaccinations are not without risk, some say. Why should the evil government compel me to expose my child to a known risk, they ask. Why is it my problem if someone else&#8217;s child is not vaccinated, they argue.<\/p>\n<p>Well&#8230; it boils down to simple math, really. Suppose that once infected, a person remains infectious for a period of time denoted by \\(\\delta t\\). The virulence of the disease is measured by the number of people that a single patient can infect during this period of time. It is called the <a href=\"https:\/\/en.wikipedia.org\/wiki\/Basic_reproduction_number\">basic reproduction number<\/a>, denoted by \\(R_0\\). If this number is greater than one, we have the potential for an epidemic.<\/p>\n<p>So then, after some time \\(t\\) has elapsed, the number \\(N(t)\\) of people who are infectious at that moment \\(N(t)=N_0R_0^{t\/\\delta t}\\), if \\(N_0\\) was the number of infected people at \\(t=0\\). At least this will be the correct number during the early stages of the epidemic; later, infection rates slow down as a growing number of people will have already caught the disease and the survivors will have developed immunity to it.<\/p>\n<p>But we are interested in the early stages indeed, because the idea is to prevent an epidemic in the first place. So this simple model is adequate.<\/p>\n<p>Now what happens when you vaccinate people? Even if everyone gets vaccinated, vaccines are not 100% effective. If the efficiency of a vaccine is given by \\(\\epsilon\\) (a number between 0 and 1, with 1 meaning 100% efficiency), the aforementioned formula is modified: \\(N(t)=[(1-\\epsilon)R_0]^{t\/\\delta t}\\). If \\((1-\\epsilon)R_0&lt;1\\), we win: an epidemic is avoided.<\/p>\n<p>But what happens when not everyone gets vaccinated? Some people obviously cannot be: very young babies, people with compromised immune systems, etc. Let&#8217;s say the vaccination rate is given by \\(\\rho\\). Once again, the formula for \\(N(t)\\) needs to be revised: \\(N(t)=[(1-\\epsilon\\rho)R_0]^{t\/\\delta t}\\).<\/p>\n<p>And this is where the problem lies: if \\((1-\\epsilon\\rho)R_0&gt;1\\), the potential for an epidemic exists.<\/p>\n<p><a href=\"http:\/\/www.bbc.com\/news\/health-24519949\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-6622\" src=\"https:\/\/spinor.info\/weblog\/wp-content\/uploads\/2015\/02\/measles.png\" alt=\"measles\" width=\"692\" height=\"438\" srcset=\"https:\/\/spinor.info\/weblog\/wp-content\/uploads\/2015\/02\/measles.png 692w, https:\/\/spinor.info\/weblog\/wp-content\/uploads\/2015\/02\/measles-300x190.png 300w\" sizes=\"(max-width: 692px) 100vw, 692px\" \/><\/a><\/p>\n<p>Take the case of measles, for which \\(R_0=12&#8230;18\\). Even if we take the lower limit of the given range, \\(R_0=12\\), it is one of the most virulent contagious diseases out there. The measles vaccine is supposedly 95% effective: \\(\\epsilon=0.95\\). So then, \\((1-\\epsilon)R_0=0.6\\), and we are good: in a fully vaccinated population, measles would disappear in short order. This is indeed what happened when measles vaccinations became common in much of the world starting in the 1970s.<\/p>\n<p>But now, let us think about \\(\\rho\\). The math is easy: If \\(\\rho&lt;0.965\\) (that is, if more than 3.5% of the population are unvaccinated), \\((1-\\epsilon\\rho)R_0&gt;1\\). Herd immunity is lost: the disease spreads.<\/p>\n<p>And lest we forget, measles is a very deadly disease. Parents who play Russian roulette with their children on the basis of unsubstantiated fears concerning the vaccine&#8217;s effectiveness and side effects forget that often the only reason their child survives the infection is because they have access to first-world health care&#8230; the same health care that would have prevented the illness in the first place, if not for the parents&#8217; arrogant stupidity.<\/p>\n<p>These parents should be reminded that in poorer parts of the world, their counterparts\u00a0often risk their lives to get their children vaccinated.\u00a0Like <a href=\"http:\/\/www.theglobeandmail.com\/globe-debate\/editorials\/the-science-is-clear-anti-vaxxers-are-immune-to-the-truth\/article22987563\/\">parents in Somalia<\/a> who, defying a ban on polio vaccination by al-Shabaab, smuggle their children to government-controlled areas to get the life-saving vaccine. Obviously these Somali parents are a lot smarter, a lot wiser than first-world anti-vaxxers, be it new age parents who prefer &#8220;happy thoughts&#8221; (or whatever) over medically approved methods, or nutty right-wingers who distrust the government on everything.<\/p>\n<p>In short, if your political or religious views, or your scientific illiteracy compel you to be as stupid as a doorknob, please find a way to express your stupidity without endangering the health and lives of others.<\/p>\n<fb:like href='https:\/\/spinor.info\/weblog\/?p=6621' send='true' layout='standard' show_faces='true' width='450' height='65' action='like' colorscheme='light' font='lucida grande'><\/fb:like>","protected":false},"excerpt":{"rendered":"<p>Vaccinations are not without risk, some say. Why should the evil government compel me to expose my child to a known risk, they ask. Why is it my problem if someone else&#8217;s child is not vaccinated, they argue. Well&#8230; it boils down to simple math, really. Suppose that once infected, a person remains infectious for <a href='https:\/\/spinor.info\/weblog\/?p=6621' class='excerpt-more'>[&#8230;]<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[29,5],"tags":[],"class_list":["post-6621","post","type-post","status-publish","format-standard","hentry","category-health","category-politics","category-29-id","category-5-id","post-seq-1","post-parity-odd","meta-position-corners","fix"],"_links":{"self":[{"href":"https:\/\/spinor.info\/weblog\/index.php?rest_route=\/wp\/v2\/posts\/6621","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spinor.info\/weblog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spinor.info\/weblog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spinor.info\/weblog\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/spinor.info\/weblog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=6621"}],"version-history":[{"count":19,"href":"https:\/\/spinor.info\/weblog\/index.php?rest_route=\/wp\/v2\/posts\/6621\/revisions"}],"predecessor-version":[{"id":6642,"href":"https:\/\/spinor.info\/weblog\/index.php?rest_route=\/wp\/v2\/posts\/6621\/revisions\/6642"}],"wp:attachment":[{"href":"https:\/\/spinor.info\/weblog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=6621"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spinor.info\/weblog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=6621"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spinor.info\/weblog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=6621"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}